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Effect of dairy and nondairy snacks on postprandial blood glucose regulation in 9-14-year-old children.

Authors
  • Gheller, Brandon J1
  • Gheller, Mary1
  • Li, Athena1
  • Nunes, Fernando2
  • Anini, Younes3
  • Glanville, N Theresa1
  • Bellissimo, Nick4
  • Hamilton, Jill5
  • Anderson, G Harvey6
  • Luhovyy, Bohdan L1
  • 1 Department of Applied Human Nutrition, Mount Saint Vincent University, 166 Bedford, Hwy, Halifax, NS B3M 2J6, Canada. , (Canada)
  • 2 Department of Child and Youth Studies, Mount Saint Vincent University, Halifax, NS B3M 2J6, Canada. , (Canada)
  • 3 Department of Obstetrics and Gynaecology, Department of Physiology and Biophysics, Dalhousie University, 6299 South St., Halifax, NS B3H 4R2, Canada. , (Canada)
  • 4 School of Nutrition, Ryerson University, 350 Victoria St, Toronto, ON M5B 2K3, Canada. , (Canada)
  • 5 Department of Paediatrics, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada. , (Canada)
  • 6 Department of Nutritional Sciences, Department of Physiology, Faculty of Medicine, University of Toronto, 27 King's College Cir, Toronto, ON M5S, Canada. , (Canada)
Type
Published Article
Journal
Applied Physiology Nutrition and Metabolism
Publisher
Canadian Science Publishing
Publication Date
Oct 01, 2019
Volume
44
Issue
10
Pages
1073–1080
Identifiers
DOI: 10.1139/apnm-2018-0549
PMID: 30794429
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

In adults, dairy consumption improves short-term blood glucose regulation. It is unknown if these short-term benefits extend to children of different weight statuses. The objective of this study was to investigate the effect of a dairy and nondairy snack in both normal-weight (NW) and overweight/obese (OW/OB) children on blood glucose regulation and food intake (FI). In a repeated-measures crossover design, 11 NW and 7 OW/OB children (age: 9-14 years), consumed, in random order, a dairy (Greek yogurt, 198.9 g, 171 kcal, 0 g fat, 17 g protein) or nondairy (mini sandwich-type cookies, 37.5 g, 175 kcal, 7.5 g fat, 1.3 g protein) snack containing 25 g of available carbohydrates. Ad libitum FI was measured 120 min after snack consumption. Blood glucose, insulin, C-peptide, and glucagon-like peptide-1 (GLP-1) were measured at 0 min (before the snack), and at 30, 60, 90, and 120 min after snack consumption. Insulin secretion was calculated from deconvolution of C-peptide. Hepatic insulin extraction was calculated as C-peptide divided by insulin. FI did not differ between snacks (P = 0.55). Mean blood glucose was lower (P < 0.001) and insulin higher (P < 0.0001) in the 120 min after consuming the dairy snack. C-Peptide concentrations (P = 0.75) and insulin secretion (P = 0.37) were not different between snacks. The increase in insulin was explained by reduced hepatic insulin extraction (P < 0.01). Consumption of the dairy snack also increased mean GLP-1 concentrations (P < 0.001). In conclusion, consumption of a dairy snack by NW and OW/OB children results in reduced postprandial blood glucose concentrations and elevated circulating insulin compared with a nondairy snack possibly because of delayed hepatic insulin extraction.

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