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[The effect of chromium picolinate on the liver levels of trace elements].

Authors
  • Aguilar, M V
  • Jorge, A M
  • Mateos, C J
  • García, J
  • Laborda, J M
  • Meseguer, I
  • Martínez-Para, M C
  • González, M J
Type
Published Article
Journal
Nutrición hospitalaria
Publication Date
Jan 01, 1995
Volume
10
Issue
6
Pages
373–376
Identifiers
PMID: 8599624
Source
Medline
License
Unknown

Abstract

Chromium picolinate has been implicated as a lipid and carbohydrate reducing agent, and therefore it may be a valuable adjunct to the treatment and prevention of diabetes and heart disease. This compound is inexpensive and apparently nontoxic. In this work, we have determined the influence of its administration (100, 200, 500 micrograms Cr/ml, for 7 and 21 days) on hepatic content of Zn, Mn, Cu and Fe of male Wistar rats. The results show a variation of the levels of these elements after the administration of chromium picolinate, although the differences are only significantly (p < 0.01) in the case of Mn. This influence is dose-dependent, occurring a decrease of 72% in the group treated with 500 micrograms/ml (Pic-500) respect to the content of control group.

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