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[Effect of carvedilol on ryanodine receptor in heart failure].

Authors
  • Li, Rong
  • Yi, Qi-jian
  • Qian, Yong-ru
  • Liu, Xiao-yan
Type
Published Article
Journal
Zhonghua er ke za zhi. Chinese journal of pediatrics
Publication Date
Aug 01, 2005
Volume
43
Issue
8
Pages
603–607
Identifiers
PMID: 16191273
Source
Medline
License
Unknown

Abstract

There is more cardiac Ca(2+) leak in HF. Carvedilol can inhibite Ca(2+) leak by restoring the contactation of FKBP12.6 back to RyR in HF to improve cardiac function and prevent left ventricle from remodeling.

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