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[Effect of antisurvivin oligodeoxynucleotides on proliferation and apoptosis in gastric cancer cell line BGC-823 and the molecular mechanism].

Authors
  • Li, Yong
  • Fan, Li-qiao
  • Sun, Yan
  • Zhao, Qun
  • Tan, Bi-bo
  • Liu, Yu
Type
Published Article
Journal
Zhonghua zhong liu za zhi [Chinese journal of oncology]
Publication Date
Apr 01, 2011
Volume
33
Issue
4
Pages
265–269
Identifiers
PMID: 21575496
Source
Medline
License
Unknown

Abstract

Survivin ASODN can induce apoptosis and inhibit the proliferation of gastric cancer cell line BGC-823 cells. Those effects are induced through up-regulation of Smac/DIABLO and down-regulation of survivin and VEGF expression simultaneously.

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