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Effect of anemia and renal cytokine production on erythropoietin production during blood-stage malaria.

Authors
  • Chang, Kai-Hsin
  • Stevenson, Mary M
Type
Published Article
Journal
Kidney international
Publication Date
May 01, 2004
Volume
65
Issue
5
Pages
1640–1646
Identifiers
PMID: 15086902
Source
Medline
License
Unknown

Abstract

Blood-stage malaria infection modulates the production of renal pro- and anti-inflammatory cytokines in resistant versus susceptible strains of mice differentially. However, despite the fluctuations of renal cytokines, the degree of anemia is the main determinant for Epo production during blood-stage malaria while kidney cytokines may exert secondary influences.

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