Affordable Access

Effect of acute changes in glucose concentration on neuronal activity and plasticity in the rat hippocampus.

Authors
  • Youssef, F F
  • Manswell, S
  • Homeward, L
Type
Published Article
Journal
West Indian Medical Journal
Publisher
West Indian Medical Journal
Publication Date
Nov 01, 2009
Volume
58
Issue
5
Pages
410–416
Identifiers
PMID: 20441057
Source
Medline
License
Unknown

Abstract

Acute changes in glucose concentration have a limited impact on neuronal transmission unless concentrations drop below 2 mM. However there seems to be little impairment of synaptic plasticity even at very low concentrations of glucose. We suggest that short term acute changes in glucose concentrations may not contribute directly to the cognitive decline associated with diabetes unless extremely severe.

Report this publication

Statistics

Seen <100 times