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Tissue response to intraperitoneal asbestos with preliminary report of acute toxicity of heat-treated asbestos in mice

Authors
Journal
Environmental Research
0013-9351
Publisher
Elsevier
Publication Date
Volume
1
Issue
3
Identifiers
DOI: 10.1016/0013-9351(67)90014-x
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Intraperitoneal asbestos not only produced fibrosis, but a special and peculiar type of fibrosis which was proliferative, granulomatous and invasive, and histologically similar to mesothelioma, although morphologic evidence of actual malignancy was not obtained. Further, asbestos fibers exposed to high temperature produced a high degree of toxicity in experimental animals; this resulted in a 60% mortality rate.

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