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Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya.

Authors
  • Eisenberg, Dan T A1
  • Campbell, Benjamin
  • Gray, Peter B
  • Sorenson, Michael D
  • 1 Department of Anthropology, Northwestern University, Evanston, IL, USA. [email protected]
Type
Published Article
Journal
BMC Evolutionary Biology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jun 10, 2008
Volume
8
Pages
173–173
Identifiers
DOI: 10.1186/1471-2148-8-173
PMID: 18544160
Source
Medline
License
Unknown

Abstract

Our results indicate that the DRD4/7R allele may be more advantageous among nomadic than settled Ariaal men. This result suggests that a selective advantage mediated through behaviour may be responsible for the higher frequency of the 7R alleles in nomadic relative to sedentary populations around the world. In contrast to previous work, we did not find an association between DRD2 genotypes and height. Our results support the idea that human phenotypic expression of genotypes should be rigorously evaluated in diverse environments and genetic backgrounds.

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