Affordable Access

Publisher Website

Technetium-99m dimercaptosuccinic acid uptake in long-term catheterized kidney:Comparison with renal function

Authors
Journal
Urology
0090-4295
Publisher
Elsevier
Publication Date
Volume
31
Issue
4
Identifiers
DOI: 10.1016/0090-4295(88)90092-1
Keywords
  • Investigative Urology

Abstract

Abstract We studied 23 long-term catheterized kidneys in 14 patients. The uptake ot 99mtechnetium dimercaptosuccinic acid ( 99mTc-DMSA) was measured at one- and two-hour intervals after injection, and the uptake was corrected for variations in renal depth. These values were compared with inulin, creatinine, and para-amino hippurate (PAH) clearances which were measured in each kidney by collecting urine through long-term catheterization. Correlation coefficient was obtained between PAH clearance corrected for the body surface area and the two-hour uptake of 99mTc-DMSA. The correlation coefficients between the two-hour uptake of 99mTc-DMSA and the clearance values are not significantly different from those between the one-hour uptake and the clearance values. Corrections of the uptake for variations in renal depth did not improve the correlation coefficients. The results show that 99mTc-DMSA is an excellent method to estimate the renal plasma flow and the one-hour uptake without correction for renal depth is clinically sufficient to evaluate the split renal function.

There are no comments yet on this publication. Be the first to share your thoughts.