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Recurrent Aphthous Stomatitis

Authors
Journal
Dental Clinics of North America
0011-8532
Publisher
Elsevier
Volume
58
Issue
2
Identifiers
DOI: 10.1016/j.cden.2013.12.002
Keywords
  • Aphthous
  • Immunologic
  • Crohn Disease
  • Behçet Disease
  • Nutritional Deficiency
  • Psychological Stress
  • Topical Therapy
  • Systemic Therapy
Disciplines
  • Medicine

Abstract

Recurrent aphthous stomatitis (RAS) is the most common ulcerative disease affecting the oral mucosa. RAS occurs mostly in healthy individuals and has an atypical clinical presentation in immunocompromised individuals. The etiology of RAS is still unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial factors, as well as immunosuppressive drugs, have been proposed as causative agents. Clinical management of RAS using topical and systemic therapies is based on severity of symptoms and the frequency, size, and number of lesions. The goals of therapy are to decrease pain and ulcer size, promote healing, and decrease the frequency of recurrence.

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