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Early prediction of response to intravenous iron supplementation by reticulocyte haemoglobin content and high-fluorescence reticulocyte count in haemodialysis patients.

Authors
Type
Published Article
Journal
Nephrology Dialysis Transplantation
0931-0509
Publisher
Oxford University Press
Publication Date
Volume
18
Issue
2
Pages
370–377
Identifiers
PMID: 12543894
Source
Medline

Abstract

Our study shows that changes in CHr and HFR at either 2 or 4 weeks are superior to the conventional erythrocyte and iron metabolism indices and may serve as reliable parameters to detect iron-deficient erythropoiesis in HD patients undergoing rHuEpo therapy. During aggressive IVFE treatment, early identification of non-responsiveness and subsequent discontinuation of treatment can avoid the inadvertent iron-related toxicity due to over-treatment.

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