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Early-onset EBV-positive post-transplant plasmablastic lymphoma arising in a liver allograft: a case report and literature review.

Authors
  • Benítez, Carlos E
  • Rey, Paula
  • Zoroquiaín, Pablo
  • Martínez, Jorge
  • Ramírez, Pablo
  • Arrese, Marco
  • Pérez-Ayuso, Rosa María
  • Valbuena, José R
Type
Published Article
Journal
International journal of surgical pathology
Publication Date
Aug 01, 2013
Volume
21
Issue
4
Pages
404–410
Identifiers
DOI: 10.1177/1066896912467371
PMID: 23222808
Source
Medline
Keywords
License
Unknown

Abstract

We report a case of a 51-year-old man who received a cadaveric liver allograft for autoimmune and hepatopulmonary syndrome. The patient was admitted with symptoms of progressive vomiting and diarrhea 16 months after transplantation. Laboratory studies showed abnormal liver functions, and abdominal magnetic resonance imaging (MRI) showed a 76-mm heterogeneous mass in the liver. Histological examination showed a malignant lymphoid neoplasm with plasmablastic features. Plasmablastic lymphoma (PL) is rare in the post-transplantation period. To the best of our knowledge, only 25 well-documented cases of posttransplant PL, including ours, have been described.

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