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Early intervention with second-generation antipsychotics in first-episode psychosis: results of an 8-week naturalistic study.

Authors
  • Josiassen, Richard C
  • Shaughnessy, Rita A
  • Filymer, Dawn M
  • Donohue, Ann Marie
  • Kacso, Margit
  • Finkel, Naomi
  • Curtis, Jessica
  • Audino, Brett
  • Skuban, Nina
Type
Published Article
Journal
Early Intervention in Psychiatry
Publisher
Wiley (Blackwell Publishing)
Publication Date
Feb 01, 2010
Volume
4
Issue
1
Pages
57–63
Identifiers
DOI: 10.1111/j.1751-7893.2010.00163.x
PMID: 20199481
Source
Medline
License
Unknown

Abstract

Early intervention with low doses of four SGAs led to rapid symptom reduction in first-episode psychotic patients with severe psychopathology. Although no clear medication advantages were observed in the short term, longer duration studies with larger samples will be required for determining efficacy, rates of compliance, relapse prevention and diminished incidence of extrapyramidal signs and symptoms.

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