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Early changes in adipokine levels and baseline limb fat may predict HIV lipoatrophy over 2 years following initiation of antiretroviral therapy.

Authors
  • Calmy, A1
  • Carey, D
  • Mallon, P W G
  • Wand, H
  • Law, M
  • Cooper, D A
  • Carr, A
Type
Published Article
Journal
HIV medicine
Publication Date
Feb 01, 2008
Volume
9
Issue
2
Pages
101–110
Identifiers
DOI: 10.1111/j.1468-1293.2007.00527.x
PMID: 18257772
Source
Medline
License
Unknown

Abstract

In ART-naïve men, higher baseline limb fat and an early increase in leptin concentrations may predict the subsequent development of lipoatrophy. We did not find the same risk factors in the two different groups of patients with peripheral fat loss and central fat gain, suggesting a partially independent pathogenesis.

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