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EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.

Authors
  • Sciagrà, Roberto1
  • Lubberink, Mark2, 3
  • Hyafil, Fabien4, 5
  • Saraste, Antti6, 7
  • Slart, Riemer H J A8, 9
  • Agostini, Denis10
  • Nappi, Carmela11
  • Georgoulias, Panagiotis12
  • Bucerius, Jan13
  • Rischpler, Christoph14
  • Verberne, Hein J15
  • 1 Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy. [email protected] , (Italy)
  • 2 Radiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. , (Sweden)
  • 3 Medical Physics, Uppsala University Hospital, Uppsala, Sweden. , (Sweden)
  • 4 Department of Nuclear Medicine, DMU IMAGINA, APHP, Hôpital Européen Georges-Pompidou, University of Paris, Paris, France. , (France)
  • 5 Université de Paris, PARCC, INSERM 690, Paris, France. , (France)
  • 6 Turku PET Centre, Turku University Hospital, University of Turku, Turku, Finland. , (Finland)
  • 7 Heart Center, Turku University Hospital, Turku, Finland. , (Finland)
  • 8 Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands. , (Netherlands)
  • 9 Faculty of Science and Technology Biomedical, Photonic Imaging, University of Twente, Enschede, The Netherlands. , (Netherlands)
  • 10 Department of Nuclear Medicine, CHU Cote de Nacre, Normandy University, EA 4650, Caen, France. , (France)
  • 11 Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy. , (Italy)
  • 12 Department of Nuclear Medicine, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, Larissa, Greece. , (Greece)
  • 13 Department of Nuclear Medicine, University Medicine Göttingen, Georg-August University Göttingen, Göttingen, Germany. , (Germany)
  • 14 Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. , (Germany)
  • 15 Department of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands. , (Netherlands)
Type
Published Article
Journal
European Journal of Nuclear Medicine
Publisher
Springer-Verlag
Publication Date
Apr 01, 2021
Volume
48
Issue
4
Pages
1040–1069
Identifiers
DOI: 10.1007/s00259-020-05046-9
PMID: 33135093
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming widely available and because several studies have convincingly demonstrated the advantages of this imaging approach. Therefore, there is a need of determining the procedural modalities for performing high-quality studies and obtaining from this demanding technique the most in terms of both measurement reliability and clinical data. Although the field is rapidly evolving, with progresses in hardware and software, and the near perspective of new tracers, the EANM Cardiovascular Committee found it reasonable and useful to expose in an updated text the state of the art of quantitative myocardial perfusion PET, in order to establish an effective use of this modality and to help implementing it on a wider basis. Together with the many steps necessary for the correct execution of quantitative measurements, the importance of a multiparametric approach and of a comprehensive and clinically useful report have been stressed.

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