Affordable Access

Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula Rezt

Authors
Publisher
Bangladesh Pharmacological Society
Publication Date
Keywords
  • Chemistry
  • Pharmacology
  • Pharmacy
  • Colon Cancer
  • Cytotoxicity
  • Endophytic Fungus
Disciplines
  • Medicine

Abstract

Endophytic microorganisms are fungi or bacteria that live inside the healthy tissues of the host plants causing no apparent symptoms of diseases. Five endophytic fungal strains labeled as IR-1, IR-2, IR-4, IR-6 and IR-7 (identified as Penicillium thiomii) were isolated from the medicinal plant of Terminalia chebula Retz by culture and sub-culture. The ethyl acetate extract of fungal strains, IR-4, IR-6 and IR-7 inhibited the growth of CaCo-2 colon cancer cell lines in MTT assay with IC50 values of 55, 44 and 67 µg/mL, respectively.DOI: http://dx.doi.org/10.3329/bjp.v7i1.10507

There are no comments yet on this publication. Be the first to share your thoughts.