Affordable Access

Vascular Endothelium Growth Factor, Surgical Delay, and Skin Flap Survival

Authors
Publication Date
Source
PMC
Keywords
  • Original Articles And Discussions
Disciplines
  • Biology
  • Pharmacology

Abstract

Surgical delay is a clinical strategy that can improve flap survival by prior partial flap elevation. Cytokine up-regulation may play roles in initiating vasodilation and angiogenesis in the delay phenomenon. In a rat myocutaneous flap model, surgical delay was associated with increased expression of vascular endothelium growth factor (VEGF) and increased flap survival. Cytokine manipulation may offer routes of pharmacological delay.

There are no comments yet on this publication. Be the first to share your thoughts.