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Organophosphates and health. - Lakshman Karalliedde, Stanley Feldman, John Henry and Timothy Marrs

The Sri Lanka Medical Association
Publication Date
  • Economics


pg77 77Vol. 47, No. 2, June 2002 Book review It is a pleasure to see this book published by the Imperial College Press with Lakshman Karalliedde as the first editor. This is the second major book edited by him, the first being Handboook of drug interactions with Professor John Henry as co-editor and running into 935 pages, published by Arnold of London. Organophosphates and health has 17 chapters, of which no less than 4 have been contributed by Karalliedde along with another in each chapter. These are entitled socio- economic health issues and pesticides, the acute cholin- ergic syndrome, management of organophosphorus compound poisoning and the global picture of organo- phosphate compound poisoning. The book appears to be a continuation of the work he did in Sri Lanka with Professor Nimal Senanayake on organophosphates. In fact, the two of them jointly wrote a paper in the New England Journal of Medicine in 1987 on what they termed the intermediate syndrome. This name given by them has stuck to the syndrome worldwide, and this book contains a chapter on the intermediate syndrome written by Jan L de Bleecker. They had the distinction of seeing the leading article in the same issue of the New England Journal of Medicine devoted to the subject described by them. This paper, as well as others written by them individually or combination, is referred to several times in the book by various authors of different chapters. Besides Karalliedde the only other Sri Lankans to figure as authors in this book are Professor Nimal Senanayake and Professor R Swaminathan. Swaminathan, along with Karalliedde are working at Guy’s Kings St Thomas Hospital Trust and Medical Schools, London. Senanayake has written the chapter on organophospho- rus-induced delayed polyneuropathy. When Karalliedde was working in Sri Lanka as Senior Lecturer in Anaes- thesiology at the Faculty of Medicine, Peradeniya, he and Senanayake worked together on organophosphates. They jointly won the President's Award given

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