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Repression of UV induction of λ prophage by caffeine

Authors
Journal
Mutation Research Letters
0165-7992
Publisher
Elsevier
Publication Date
Volume
119
Issue
1
Identifiers
DOI: 10.1016/0165-7992(83)90030-1

Abstract

Abstract Caffeine was found to function as a repressor of UV-induced λ prophage when added to the post-irradition culture medium with both uvrB + and uvrB − strains of E. coli K12. Caffeine functioned as a repressor of λ induction at high but not low inducing doses of UV. Caffeine alone at concentrations above 10 mg/plate functioned as an inducer of λ prophage.

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