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Effect of Cu(II)-aminopolycarboxylates on the radiosensitivity of thymine

Authors
Journal
International Journal of Radiation Applications and Instrumentation Part C Radiation Physics and Chemistry
1359-0197
Publisher
Elsevier
Publication Date
Volume
37
Issue
2
Identifiers
DOI: 10.1016/1359-0197(91)90152-r

Abstract

Abstract Relative degradation of thymine (T) on radiolysis was found to be enhanced appreciably in the presence of Cu(II)-aminopolycarboxylate complexes. However the role of Cu(II) complexes in affecting the radiosensitivity of thymine was found to be markedly different than when copper was used as a simple salt, e.g. copper sulphate. A probable reaction mechanism relating the formation of products and the degradation of thymine in these systems has been proposed.

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