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The Physical Aspects of Radioisotopic Organ Imaging

British Journal of Cancer
Nature Publishing Group
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  • Book Review
  • Biology
  • Education
  • Medicine


152 BOOK REVIEWS evaded by many authors including those of the WHO Atlas (No. 8 in the "International Histological Classification of Tumours"). What name should be applied to the type of cell which comes off the surface layers of carcinoma in situ of the cervix? In the section of this book concerning carcinoma in situ they are called "malignant cells"; but in the previous section on severe dys- plasia, cells which admittedly may be indis- tinguishable are called "severely dyskaryotic parabasal cells". Is the description "malignant cell" best made on the grounds of a particular abnormal type of chromatin distribution? If so, cells shed by a cancer which do not show this pattern must not be called malignant cells, although they are none the less can- cerous. It would be better to redefine the term "dyskaryosis" (invented by Papanico- laou and discarded by many American authorities) for all this range of cytological abnormalities, including the changes seen in fully developed carcinoma, and leave the word "malignant" for the histopathologist to use when he finds invasion. Any laboratory concerned in teaching diagnostic cytology, whether to pathologists, technologists or "screeners", will want to have this book. It is not only a useful (and, in 1977, inexpensive) source of illustrations for its purpose, but even possesses a genuine index from which you can find everything that is pictured within. A. I. SPRIGGS Protides of the Biological Fluids. Ed. H. PEETERS (1976). London: Pergamon Press. 836 pp. Subscription price $68.00. Non-subscription price $75.00. This volume contains the proceedings of the 24th Bruges Colloquium on Proteins and Related Subjects, 1976, including the 5th Tiselius Memorial Lecture delivered by Professor Ballieux of Utrecht, whose subject was "Molecules as Markers and Receptors" and who gave an overall view of those func- tions of cell-membrane proteins, taking the lymphocyte as his model. The book comprises three main sections: A. Pregnancy Associated Proteins, contain-

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