Summary A case of Parinaud's oculoglandular syndrome is described in a 7-year-old boy, who presented himself as a differential diagnostic problem of a preauricular tumor. The syndrome consists of a granulomatous conjunctivitis with associated regional lymphadenopathy. If an unexplained preauricular mass is found, the upper lid should be everted and examined for the conjunctivitis of Parinaud. Treatment with Achromycin by mouth and sulfathiazole ophthalmic ointment locally shortens the self-limited course of this syndrome. Studies necessary to demonstrate an etiological agent are reviewed and it is emphasized that laboratory confirmation is difficult even under the best circumstances.