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In vitro activity of garenoxacin against recent clinical isolates ofChlamydia pneumoniae

Authors
Journal
International Journal of Antimicrobial Agents
0924-8579
Publisher
Elsevier
Publication Date
Volume
21
Issue
6
Identifiers
DOI: 10.1016/s0924-8579(03)00061-x
Keywords
  • Chlamydiapneumoniae
  • Garenoxacin
  • Mic
  • Fluoroquinolones

Abstract

Abstract The in vitro activities of garenoxacin, a novel des-F (6)-quinolone, levofloxacin, moxifloxacin and clarithromycin were tested against 30 recent clinical isolates of Chlamydia pneumoniae. The minimal inhibitory concentration (MIC) at which 90% of the isolates were inhibited and the minimal bactericidal concentration (MBC) at which 90% of the isolates were killed by garenoxacin for C. pneumoniae was 0.03 mg/l (range 0.015–0.03 mg/l).

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