Affordable Access

Publisher Website

Effectiveness of botulinum toxin A in treatment of refractory erythromelalgia

Authors
Journal
Journal of the Chinese Medical Association
1726-4901
Publisher
Elsevier
Volume
76
Issue
5
Identifiers
DOI: 10.1016/j.jcma.2013.01.003
Keywords
  • Erythromelalgia
  • Neurogenic Inflammation
  • Neuropathic Pain
  • Onabotulinumtoxin A
  • Small-Fiber Neuropathy
Disciplines
  • Medicine

Abstract

Abstract Erythromelalgia is characterized by intense burning pain, erythema, and heat in affected areas after precipitating factors such as warm temperature or stress. It is refractory to treatment in some situations. We describe a woman with adenosquamous cell carcinoma of the lung and medically refractory erythromelalgia. The symptoms of erythromelalgia presented as refractory to any medical treatment. Due to the unresponsive nature of her condition, botulinum toxin type A (onabotulinumtoxin A) was injected over both of her cheeks, periodically for six cycles. Her symptoms responded dramatically to subcutaneous and intradermal injection of botulinum toxin type A. Repetitive injection demonstrated consistent and reproducible responses, and the efficacy was maintained for approximately 1 month. No adverse effects or complications were noted. Botulinum toxin type A might be safe and effective as an alternative treatment for refractory erythromelalgia, but further large-scale studies are required.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Effectiveness of botulinum-A toxin for the treatme...

on European journal of pediatric... May 2010

Cost-Effectiveness of Sacral Neuromodulation Versu...

on The Journal of Urology Jan 01, 2009

Botulinum toxin type A for treatment of refractory...

on American journal of health-sys... Nov 01, 2007

The use of botulinum toxin in the treatment of ref...

on Ostomy/wound management December 2006
More articles like this..