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Wrestling Rules in Transrepression: As Easy as SUMO-1, -2, -3?

Authors
Journal
Molecular Cell
1097-2765
Publisher
Elsevier
Publication Date
Volume
25
Issue
2
Identifiers
DOI: 10.1016/j.molcel.2007.01.009

Abstract

A recent study in Molecular Cell ( Ghisletti et al., 2007) uncovered parallel yet distinct SUMOylation pathways that provide insights into molecular mechanisms of transrepression mediated by activated nuclear receptors LXRα/β and PPARγ, thereby clarifying receptor, signal, and gene specificity of transrepression in inflammatory processes.

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