Affordable Access

Publisher Website

Stereocontrolled entry to 2,5-disubstituted tetrahydrofurans from hex-2-enono-δ-lactones under mild conditions

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
33
Issue
35
Identifiers
DOI: 10.1016/s0040-4039(00)61202-9

Abstract

Abstract A stereospecific route to highly functionalized 2,5-disubstituted tetrahydrofuran derivatives from readily available 6-O-silylated-hex-2-enono-δ-lactones is reported. The protocol involves an efficient Michael type O-heterocyclization reaction followed by selective ring opening of the lactone moiety.

There are no comments yet on this publication. Be the first to share your thoughts.