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Addition of molecular fluorine to bicyclo[2.2.1]hept-2-ene derivatives and conversion to fluorine-containing carbocyclic nucleosides

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
35
Issue
31
Identifiers
DOI: 10.1016/s0040-4039(00)77274-1

Abstract

Abstract Addition of molecular fluorine to bicyclo[2.2.1]hept-2-ene derivatives has been found to give exo,exo-difluoro adducts in fair yields. The difluoro adduct ( 13c) was converted to the fluorine containing carbocyclic adenosine and guanosine analogs.

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