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An enantioselective synthesis of a key intermediate to thienamycin by chemicoenzymatic approach

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
29
Issue
9
Identifiers
DOI: 10.1016/0040-4039(88)85334-6
Disciplines
  • Chemistry

Abstract

Abstract A key intermediate to thienamycin is synthesized enantioselectively under complete stereo- and regio-chemical control starting from a chiral half ester 5 enzymatically generated.

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