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Influence of serum on attachment of tissue cells to glass surfaces

Authors
Journal
Experimental Cell Research
0014-4827
Publisher
Elsevier
Publication Date
Volume
70
Issue
1
Identifiers
DOI: 10.1016/0014-4827(72)90179-6

Abstract

Abstract In serum-free medium, human diploid cells (MRC-5) spread more rapidly on glass surfaces than when serum is present, and the morphology of the cells throughout spreading is affected by the presence or absence of serum. It is suggested that a possible role of serum in tissue culture media is to modify either the cell or glass surfaces so that the cell is able to overcome forces that arise between cell and glass from surface charge effects.

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