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HISTOLOGY OF THE URETHRAL PLATE: IMPLICATIONS FOR HYPOSPADIAS REPAIR

Authors
Journal
The Journal of Urology
0022-5347
Publisher
Elsevier
Publication Date
Volume
164
Issue
3
Identifiers
DOI: 10.1016/s0022-5347(05)67233-3
Keywords
  • Urethra
  • Hypospadias
  • Penis
  • Histology
Disciplines
  • Biology
  • Medicine

Abstract

Purpose We define the histology of the urethral plate in boys with hypospadias. Materials and Methods Subepithelial biopsies of the urethral plate were obtained in 17 boys, including 13 with distal and 4 with penoscrotal hypospadias. Ventral penile curvature was noted in 5 cases. Specimens were evaluated by 7 light microscopy after hematoxylin and eosin staining. Results All biopsies demonstrated well vascularized connective tissue comprised of smooth muscle and collagen. There was no evidence of fibrous bands or dysplastic tissue. Conclusions The urethral plate consists of epithelium overlying connective tissue. We found no histological evidence of fibrous cords historically considered responsible for chordee.

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