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Linezolid resistance in a clinical isolate ofStaphylococcus aureus

Authors
Journal
The Lancet
0140-6736
Publisher
Elsevier
Publication Date
Volume
358
Issue
9277
Identifiers
DOI: 10.1016/s0140-6736(01)05410-1
Keywords
  • Primary Research
  • Research Letters

Abstract

Summary The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.

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