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Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids.

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  • Rhizopus Delemar Lipase Catalyzed Ester Hydrolysis Of The Alpha-Methoxy-Beta-Phenylpropanoate (I) Af
  • 84% Enantiomeric Excess
  • Abs
  • Stereochem
  • Was Detd
  • By A Single Crystal X-Ray Anal
  • Of A Related Synthetic Analog
  • The Activity Of These Two Enantiomers On Glucose Transport In Vitro And As Anti-Diabetic Agents In V
  • Binding Studies Using Recombinant Human Ppar-Gamma (Peroxisomal Proliferator Activated Receptor Gamm
  • Now Established As A Mol
  • Target For This Compd
  • Class
  • Indicate A 20-Fold Higher Binding Affinity For The (S) Antipode Relative To The (R) Antipode


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