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Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

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Publication Date
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PMC
Keywords
  • Corrigendum
Disciplines
  • Biology

Abstract

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance Corrigenda Cullin-based ubiquitin ligases: Cul3–BTB complexes join the family Lionel Pintard, Andrew Willems and Matthias Peter The EMBO Journal (2005) 24, 1092. doi:10.1038/sj.emboj.7600623 Correction to: The EMBO Journal (2004) 23, 1681–1687. doi:10.1038/sj.emboj.7600186 Due to redundant and confusing nomenclature, the authors have introduced a mistake in the above review. In this review, they list Smac3/Diablo proteins, involved in apoptosis, as BTB/Kelch proteins. Partly based on this point, they speculate that these proteins might act as substrate-specific adaptors of Cul-3 based E3-ligases. It appears that this protein is distinct from another BTB/Kelch-containing protein also called Diablo. Therefore, the authors’ speculation that Cul-3 based ligases could play a role in apoptosis is not correct and misleading. The authors apologize for this error. Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance Supriya G Prasanth, Kannanganattu V Prasanth, Khalid Siddiqui, David L Spector and Bruce Stillman The EMBO Journal (2005) 24, 1092–1093. doi:10.1038/sj.emboj.7600624 Correction to: The EMBO Journal (2004) 23, 2651–2663. doi:10.1038/sj.emboj.7600255 Due to an author error, the X-axis in Figure 3D was mislabelled as INA instead of DNA. The correct figure is reproduced below. The authors apologize for this error. The EMBO Journal (2005) 24, 1092–1093 | & 2005 European Molecular Biology Organization |All Rights Reserved 0261-4189/05 www.embojournal.org The EMBO Journal VOL 24 | NO 5 | 2005 &2005 European Molecular Biology Organization EMBO THE EMBO JOURNAL THE EMBO JOURNAL 1092 Figure 3 Orc2 depletion has dual execution points. (A) Immunoblot of whole-cell extract from cells transfected with Orc2 siRNA duplex or control luciferase siRNA and harvested at different time points. Cells were transf

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