Affordable Access

Publisher Website

Facile synthesis of acacetin-7-O-β-d-galactopyranoside

Authors
Journal
Carbohydrate Research
0008-6215
Publisher
Elsevier
Publication Date
Volume
348
Identifiers
DOI: 10.1016/j.carres.2011.11.015
Keywords
  • Acacetin-7-O-β-D-Galactopyranoside
  • Flavonoid
  • Aglycon
  • Glycosyl Fluoride
  • O-Glycosylation

Abstract

Abstract Acacetin-7- O-β- d-galactopyranoside ( 1), a natural flavonoid isolated from flower heads of Chrysanthemum morifolium, has been reported to inhibit the replication of HIV in H9 cells. We achieved the total synthesis of compound 1 by employing a one-pot synthesis of the aglycon. The key reactions in this approach include the modified Baker–Venkataraman reaction and regio- and stereoselective O-glycosylations.

There are no comments yet on this publication. Be the first to share your thoughts.