Affordable Access

Sterol biosynthesis via lanosterol by the trypanosomidCrithidia fasciculata

Authors
Journal
FEMS Microbiology Letters
0378-1097
Publisher
Oxford University Press
Publication Date
Keywords
  • Sterol Biosynthesis
  • Lanosterol
  • 31-Norlanosterol
  • Crithidia Fasciculata
  • Trypanosomidae

Abstract

Abstract Incorporation of [1- 14 C]acetate by the trypanosomid Crithidia fasciculata showed that ergosterol biosynthesis occurs de novo in this protozoon, via lanosterol and 31-norlanosterol. No cycloartenol could be detected, indicating that this biosynthesis pathway is rather similar to those of other non-photosynthetic organisms (animals, fungi). From the point of view of sterol biosynthesis, C. fasciculata is not related to other ergosterol-synthesising protozoa, such as the hitherto examined phytoflagellates and soil amoebae, which synthesise their sterols via cycloartenol, like photosynthetic organisms (plants, algae).

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Lanosterol biosynthesis in the prokaryote Methyloc...

on Molecular Biology and Evolutio... August 2007

Cholesterol biosynthesis from lanosterol: regulati...

on Journal of biochemistry April 1995

Cholesterol biosynthesis from lanosterol: regulati...

on Biochimica et Biophysica Acta Oct 26, 1995
More articles like this..