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THE ACTIVITY OF CYTOLYSIS ENZYMES IN ACUTE CORONARY SYNDROMES

Authors
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Analele Stiintifice ale Universitatii "Alexandru Ioan Cuza" din Iasi Sec. II a. Genetica si Biologie Moleculara
Publication Date
Disciplines
  • Biology
  • Medicine

Abstract

The determination of enzyme activity in the organism’s humours or in different tissues is an important meansof detecting and following the evolution of numerous pathological states. In our study we have determined the activity ofsome cytolysis enzymes (lactate dehydrogenase, LDH; alanine-aminotransferase or glutamic-pyruvic transaminase, GPT;aspartate aminotransferase or glutamic-oxaloacetic transaminase, GOT ; creatine kinase, CK and gamma-glutamyltranspeptidase, GGT) on patients with acute coronary syndromes : angina pectoris (AP), chronic painfulischemic heart disease (CPIHD), arterial hypertension (HTN), arterial hypertension with chronic painful ischemic heartdisease (HTN+CPIHD) and acute myocardial infarction (AMI). The results show that the levels of activity of cytolysisenzymes are different in patients with acute coronary syndromes (ACS). The activity of LDH, GPT, GOT, CK and GGTdo not have the same values for one and the same coronary disease measured in patients from different groups of age andsexes (male and female).

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