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Preparation and antigenic properties of testosterone-4-bovine serum albumin conjugates

Authors
Journal
Journal of Steroid Biochemistry
0022-4731
Publisher
Elsevier
Publication Date
Volume
10
Issue
5
Identifiers
DOI: 10.1016/0022-4731(79)90212-7
Disciplines
  • Chemistry

Abstract

Abstract New hapten-carrier conjugates were prepared from 4-hydroxytestosterone 4-hemisuccinate and 4-hemiglutarate by coupling with bovine serum album employing the mixed anhydride technique. The specificity of anti-testosterone antisera elicited in the rabbits by immunization with these antigens was tested by cross-reaction studies with the related steroids in the radioimmunoassay procedure and discussed from the stereochemical point of view.

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