Affordable Access

Publisher Website

Regioselective syntheses of trehalose-containing trisaccharides using various glycohydrolases

Authors
Journal
Carbohydrate Research
0008-6215
Publisher
Elsevier
Publication Date
Volume
199
Issue
2
Identifiers
DOI: 10.1016/0008-6215(90)84264-u
Disciplines
  • Biology

Abstract

Abstract Two methods were investigated for the enzymic preparation of trehalose-containing trisaccharides. In the first, a solution of saccharides is circulated through an immobilized-glycosidase column and an activated-carbon column connected in series. In the second, two enzymes having different substrate specificities are sequentially used for condensation and subsequent specific hydrolysis. Thus, 3- O-β- d-, 4- O-β- d-, and 6- O-β- d-galactopyranosyl- a, a-trehalose; 4- O- a- d- and 6- O- a- d-glucopyranosyl- a, a-trehalose; and 4- O-β- d- and 6- O-β- d-glucopyranosyl- a, a-trehalose were synthesized stereo- and regio-selectively.

There are no comments yet on this publication. Be the first to share your thoughts.