Yale Cancer Center: Past, Present, and Future

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Yale Cancer Center: Past, Present, and Future

Yale Journal of Biology and Medicine
  • Conclusion


Layout 1 199 YALE JOURNAL OF BIOLOGYAND MEDICINE 79 (2006), pp. 199-200. Copyright © 2006. CONCLUSION Yale Cancer Center: Past, Present, and Future Edward Chu, MD, and Richard Edelson, MD Yale University School of Medicine, New Haven, Connecticut This special issue of the Yale Journal of Biology and Medicine is composed of overviews of fundamental and clinical re- search contributions at a time when our sci- entific understanding of cancer biology is blossoming and has begun to generate large numbers of new, biologically based treat- ments. This process, referred to as “Trans- lation,” in very large measure began at the Yale School of Medicine (YSM) 60 years ago. It is therefore quite fitting that this timely and comprehensive issue has been compiled during this period of unprece- dented parallel growth in clinical and re- search facilities and translational activities. Here at Yale, a four-story cancer hospi- tal designed to set a new standard in multi- disciplinary inpatient and outpatient creative clinical care is under construction. This state-of-the-art clinical facility will be accompanied by the expansion of interac- tive laboratories to be occupied by themat- ically linked teams of Yale Cancer Center (YCC) scientists. This excitement builds on a long and rich history at YSM. The modern era of cancer chemotherapy was ushered in when Gilman, Goodman, and Lindskog used ni- trogen mustard to treat a patient with lym- phoma in 1942. In the 1950s and 1960s, researchers in the Department of Pharma- cology were the first scientists to focus on cancer chemotherapy and drug develop- ment, and, in 1965, YSM established the first university-based Department of Clini- cal Pharmacology and Chemotherapy in the United States, a forerunner to what is now known as “Medical Oncology.” The pioneering work that was con- ducted during those early days of cancer re- search at Yale laid the foundation for our understanding of a number of key classes of anticancer drugs, including the antif

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