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Noise Pollution: EU Ramps Up Road Improvements

Environmental Health Perspectives
Environmental Health Perspectives
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workingforum.qk We shape our buildings, and afterwards our buildings shape our world. Winston Churchill quoted in Ethics and the Problems of the Twenty-First Century (1979) Environews Forum A 612 VOLUME 112 | NUMBER 11 | August 2004 • Environmental Health Perspectives Mother’s Thyroid, Baby’s Health Since the 1970s, epidemiologic studies have linked maternal thyroid insufficiency dur- ing gestation with fetal brain malformation, fetal death, and miscarriage. The fetus is wholly dependent on the maternal thyroid during the first 10–20 weeks of gestation. U.S. women generally get enough iodine, the elemental nutrient essential for synthesis of the thyroid hormone thy- roxine (T4). But regular daily intake may not be sufficient during pregnancy due to metabolic changes in the mother-to-be, and recent stud- ies suggest that detection and treatment may be needed long before birth. These and other topics were discussed by scien- tists at a January 2004 sympo- sium cosponsored by the Centers for Disease Control and Prevention, the National Center on Birth Defects and Developmental Disabilities, and the American Thyroid Association (ATA). Early maternal thyroidal insufficiency, or EMTI, is a failure of the maternal thyroid to provide an adequate supply of T4 in early pregnancy. According to Steven Lamm, a pediatrician and director of the Washington, D.C.–based Consultants in Epidemiology and Occupa- tional Health, EMTI may affect 0.5–5.0% of all pregnant women. When depletion occurs early in pregnancy, fetal brain forma- tion can be markedly altered. Even subtle degrees of thyroid dysfunction in pregnant women might be associated with impaired psychomotor development in their infants, toddlers, and preschool children. While there’s no doubt that EMTI is related to poor fetal outcomes, the follow-up data on child development are only available until 5–6 years of age, so it’s still unknown whether these developmental delays persist over the long term, said Victor Pop, a pro- fessor in t

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