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Specifying Positional Information in the Embryo: Looking Beyond Morphogens

Authors
Journal
Cell
0092-8674
Publisher
Elsevier
Publication Date
Volume
130
Issue
2
Identifiers
DOI: 10.1016/j.cell.2007.06.038

Abstract

Concentration gradients of small diffusible molecules called morphogens are key regulators of development, specifying position during pattern formation in the embryo. It is now becoming clear that additional or alternative mechanisms involving interactions among cells are also crucial for positional specification.

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