In present paper, 62 cases of dysautonomia out of 115 patients with GBS. In the clinical manifestations of the dysautonomia, the disorder of heart was most (85.48%), the second was abnormality of the blood pressure and the digestive tract (both 37.1) and the abnormality of sweat and sexual dysfunction would not take less (30.65% and 17.74% respectively). It was also found that there were the facial flushing (4.84%) and abnormal pupilla (6.45%). The sexual dysfunction was firstly reported. Dysautonomia in GBS was higher in young adults (less than 20 years) (P less than 0.01) and that in the severe cases (P less than 0.01). The mortality of patients of GBS with dysautonomia was higher (P less than 0.01). The pathophysiological mechanism and treatment of GBS were discussed.