Affordable Access

Access to the full text

Dynamics in protein translation sustaining T cell preparedness

Authors
  • Wolf, Tobias1, 2
  • Jin, Wenjie1
  • Zoppi, Giada1
  • Vogel, Ian A.1
  • Akhmedov, Murodzhon1
  • Bleck, Christopher K. E.3
  • Beltraminelli, Tim1
  • Rieckmann, Jan C.4
  • Ramirez, Neftali J.5, 6
  • Benevento, Marco1
  • Notarbartolo, Samuele1
  • Bumann, Dirk3
  • Meissner, Felix4, 7
  • Grimbacher, Bodo5, 8, 9, 10
  • Mann, Matthias11
  • Lanzavecchia, Antonio1
  • Sallusto, Federica1, 2
  • Kwee, Ivo1
  • Geiger, Roger1
  • 1 Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland , Bellinzona (Switzerland)
  • 2 Institute of Microbiology, ETH Zürich, Zurich, Switzerland , Zurich (Switzerland)
  • 3 Biozentrum, University of Basel, Basel, Switzerland , Basel (Switzerland)
  • 4 Experimental Systems Immunology, Max Planck Institute of Biochemistry, Munich, Germany , Munich (Germany)
  • 5 Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany , Freiburg (Germany)
  • 6 Integrated Research Training Group (IRTG) Medical Epigenetics, Collaborative Research Centre 992, Freiburg, Germany , Freiburg (Germany)
  • 7 Institute of Innate Immunity, Department of Systems Immunology and Proteomics, Medical Faculty, University of Bonn, Bonn, Germany , Bonn (Germany)
  • 8 DZIF – German Center for Infection Research, Satellite Center Freiburg, Freiburg, Germany , Freiburg (Germany)
  • 9 CIBSS – Centre for Integrative Biological Signalling Studies, Albert-Ludwigs University, Freiburg, Germany , Freiburg (Germany)
  • 10 RESIST – Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany , Freiburg (Germany)
  • 11 Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Munich, Germany , Munich (Germany)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Jul 06, 2020
Volume
21
Issue
8
Pages
927–937
Identifiers
DOI: 10.1038/s41590-020-0714-5
Source
Springer Nature
License
Yellow

Abstract

Geiger and colleagues use SILAC and mass spectrometry to study protein turnover in human T cells and examine how naive T cells maintain their quiescence and transition to activated cells.

Report this publication

Statistics

Seen <100 times