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Dynamics of neutrophilic NF-kB translocation in relation to IL-8 mRNA expression after major trauma.

Authors
  • Stegmaier, J C
  • Kirchhoff, C
  • Bogner, V
  • Matz, M
  • Kanz, K-G
  • Mutschler, W
  • Biberthaler, P
Type
Published Article
Journal
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Publication Date
Nov 01, 2008
Volume
57
Issue
11
Pages
547–554
Identifiers
DOI: 10.1007/s00011-008-7207-6
PMID: 19109749
Source
Medline
License
Unknown

Abstract

This pilot study has shown that a concomitant initial increase in transcriptional NF-kB-activity and IL-8 mRNA expression was observed in the early posttraumatic period which preceded the down-regulation of the innate immune system.

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