Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Dynamics of gag-pol minority viral populations in naive HIV-1-infected patients failing protease inhibitor regimen.

Authors
  • Larrouy, Lucile
  • Charpentier, Charlotte
  • Landman, Roland
  • Capitant, Catherine
  • Chazallon, Corine
  • Yeni, Patrick
  • Peytavin, Gilles
  • Damond, Florence
  • Brun-Vezinet, Françoise
  • Descamps, Diane
Type
Published Article
Journal
AIDS
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Nov 13, 2011
Volume
25
Issue
17
Pages
2143–2148
Identifiers
DOI: 10.1097/QAD.0b013e32834cabb9
PMID: 21904187
Source
Medline
License
Unknown

Abstract

We highlighted the emergence of minority viral populations in the p2/p7 cleavage site between baseline and virological failure. In addition, we showed the association of a specific protease mutation with gag and gag-pol cleavage site substitutions, suggesting their possible role in virological outcome.

Report this publication

Statistics

Seen <100 times