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Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.

Authors
  • Tanaka, M
  • Uchiyama, M
  • Ikeda, S
Type
Published Article
Journal
Endoscopy
Publication Date
Aug 01, 1977
Volume
9
Issue
3
Pages
136–139
Identifiers
PMID: 913366
Source
Medline
License
Unknown

Abstract

As duodenofiberscopy becomes popular, duodenal mucosal damage associated with aspirin ingestion has come to draw more attention than before. Duodenal mucosal injury, with or without gastric lesions, related to long-term use of anti-inflammatory drugs such as aspirin, indomethacin, ibuprofen, diclofenac or others are reported in three patients, in which the diagnosis was confirmed by emergency endoscopy after hematemesis. Some possible explanations for pathogenetic mechanisms are discussed.

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