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Dual roles for transcription and translation factors in the RNA storage particles of Xenopus oocytes.

Authors
Type
Published Article
Journal
Trends in Cell Biology
0962-8924
Publisher
Elsevier
Publication Date
Volume
3
Issue
3
Pages
94–98
Identifiers
PMID: 14731778
Source
Medline

Abstract

During oogenesis, Xenopus laevis utilizes homologues of normal transcription or translation factors to sequester a variety of RNA molecules into ribonucleoprotein storage particles. This remarkable adaptive function for a diverse group of regulatory molecules allows the oocyte to stockpile macromolecules for use during embryogenesis. We discuss the special features of these nucleic acid-binding proteins and the insights into their structure and function that follow from their dual biological role.

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