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Drug-Drug Interaction Between Oxycodone and Diazepam by a Combined in silico Pharmacokinetic and Pharmacodynamic Modeling Approach

Authors
  • Ji, Beihong1, 2
  • Xue, Ying1, 2, 3
  • Xu, Yuanyuan1, 2
  • Liu, Shuhan1, 2
  • Gough, Albert H4
  • Xie, Xiang Qun1, 2
  • Wang, Junmei1, 2
  • 1 Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, The University of Pittsburgh, 3501 Terrace St, Pittsburgh, PA 15261
  • 2 NIH National Center of Excellence for Computational Drug Abuse Research, The University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, USA.
  • 3 Department of Pharmacy and Therapeutics, School of Pharmacy, The University of Pittsburgh, 3501 Terrace St, Pittsburgh, PA 15261
  • 4 Computational and Systems Biology, The University of Pittsburgh, Drug Discovery Institute, 800 Murdoch Building, 3420 Forbes Avenue, Pittsburgh, Pennsylvania, 15260, USA.
Type
Published Article
Journal
ACS Chemical Neuroscience
Publisher
American Chemical Society
Publication Date
May 05, 2021
Volume
12
Issue
10
Pages
1777–1790
Identifiers
DOI: 10.1021/acschemneuro.0c00810
PMID: 33950681
PMCID: PMC8374491
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown
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