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Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform †

Authors
  • Zhang, Yan
  • Kim, Sungho
  • Shi, Weihua
  • Zhao, Yaoyao
  • Park, Insu
  • Brenden, Christopher
  • Iyer, Hrishikesh
  • Jha, Prasoon
  • Bashir, Rashid
  • Sweedler, Jonathan V.
  • Vlasov, Yurii
Type
Published Article
Journal
Lab on a Chip
Publisher
The Royal Society of Chemistry
Publication Date
Dec 12, 2021
Volume
22
Issue
1
Pages
40–46
Identifiers
DOI: 10.1039/d1lc00758k
PMID: 34897344
PMCID: PMC8691365
Source
PubMed Central
Disciplines
  • Chemistry
License
Unknown

Abstract

We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase separation for mass spectrometry analysis.

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