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Dosing Practices of Intravenous Acyclovir for Herpes Encephalitis in Obesity: Results of a Pharmacist Survey.

Authors
  • Wong, Adrian1
  • Pickering, Aaron J2
  • Potoski, Brian A3, 4
  • 1 1 Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA, USA.
  • 2 2 Department of Pharmacy, UPMC St Margaret, Pittsburgh, PA, USA.
  • 3 3 Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.
  • 4 4 Antibiotic Management Program, UPMC Presbyterian, Pittsburgh, PA, USA.
Type
Published Article
Journal
Journal of pharmacy practice
Publication Date
Jun 01, 2017
Volume
30
Issue
3
Pages
324–328
Identifiers
DOI: 10.1177/0897190016642689
PMID: 27067742
Source
Medline
Keywords
License
Unknown

Abstract

Intravenous dosing of acyclovir for herpes encephalitis is variable, especially in obese patients, and does not reflect recommendations. Limited data provide conflicting recommendations for dosing in obese patients, and future studies are necessary to optimize patient outcomes and prevent toxicity.

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